Event announcement: Synchrony 2020 Online Symposium – Translational Research In Autism - November/December 2020

Autism Treatments – Clinical Research Trials

Autism Treatments – Clinical Research Trials

clinical trials autism research participants

Ongoing UK Clinical Trials for Autism – research studies recruiting participants

The following is a list of research trials currently taking place in the UK and actively recruiting study participants. The studies have been designed to investigate the potential of various medications and interventions to help reduce core autism symptoms, and/or difficulties and symptoms frequently experienced by individuals affected by autism such as anxiety, irritability, impulsive, aggressive and self-harming and other challenging behaviours.

Please note that the studies are not run by Thinking Autism. We can not reply to questions about the studies, the treatments themselves, or your or your child’s eligibility to take part in the trials. If you have any questions about the trials or would like your child/ren or yourself to take part in one of the studies please contact the institutions that are running the trials via the links provided.

Please note: the list is not comprehensive. If your organisation is running a trial and recruiting participants who live in the UK please contact us to have it added to the list. In order to qualify for a listing the aims and objectives of the study need to fall under one or both of the following categories: 1. reducing core symptoms of autism 2. addressing underlying or comorbid biomedical disorders that contribute to symptoms and difficulties experienced by individuals with autism.

The list will be updated on an ongoing basis. Please make sure to come back and refresh the page from time to time, or subscribe to our mailing list to be informed of future additions.

STAR-AIMS: improving social communication skills in children with autism (LONDON & UK)

STAR-AIMS is a new clinical trial investigating if a medication called arbaclofen can help improve social difficulties in children and young people with autism.

Why is the study important?
➢ To date, no medications have been approved to support social function in autism. We want to try and change this with your help.
➢ STAR-AIMS is part of AIMS-2-Trials, the largest ever research project in autism.
➢ AIMS-2-Trials and STAR-AIMS will help increase our understanding of autism and improve outcomes and quality of life for people with autism.

Information on AIMS-2 and arbaclofen

Can you or your child take part?
You must be 5 to 17 years of age and have good verbal skills
Have a confirmed diagnosis of an autism spectrum condition (ASD)
Your parent or caregiver is willing to take part in the study with you
You can visit us at one of our UK research sites for your appointments. We will reimburse your travel expenses and offer you £50 worth of vouchers at the end of the study.

Getting involved
If you think you might be interested in taking part or would like to hear more about the study, please contact your nearest STAR-AIMS team for a chat:

London: King’s College London and SLaM: 0207 848 1520 / 0207 848 5260, STAR-AIMS-2-TRIALS@kcl.ac.uk
Newcastle: Clinical Research Facility, NUTH NHS: 0191 282 0070 (to launch here soon).
Glasgow: Queen Elizabeth University Hospital: 0141 232 7600

Bumetanide for Autism treatment trial (CENTRAL LONDON & UK)

A large European multi-centre Phase III trial is currently taking place in France and several other EU countries, including the UK.

This study is investigating the effectiveness of bumetanide for treating core symptoms of autism. Children and adolescents with a diagnosis of autism or suspected diagnosis, aged 2-17 can participate.

UK centres conducting the trials:

ReCognition Health (several recruitment centres in the UK) – click here for more details and to apply

More details and results of previous bumetanide autism trials

Bumetanide for Autism treatment trial (Colchester, Essex)

A large European multi-centre Phase III trial is currently taking place in France and several other EU countries, including the UK.

This study is investigating the effectiveness of bumetanide for treating core symptoms of autism.

Can your child take part?
Children with a confirmed diagnosis of autism who are aged 2-7 years and living in Colchester can take part.
(If your child does not meet those criteria see below for other UK centres participating in bumetanide trial and recruiting older-age children).

Getting involved
This study is no longer recruiting.

More details and results of previous bumetanide autism trials

Thinking Autism blog – science news & updates

Addressing Poor Health & High Death Rates in Autism

Addressing Poor Health & High Death Rates in Autism

“We must first recognise ASD as a whole body disorder” Autism, or Autism Spectrum Disorder ASD, is traditionally seen as the result of behavioural and neuropsychiatric dysfunction. However there is a strong evidence that various physical, or biomedical, problems can...

read more
Synchrony 2019 – Translational Research in Autism symposia

Synchrony 2019 – Translational Research in Autism symposia

The first Brain Foundation annual symposia, Pleasanton, California 8-10 of Nov 2019, aimed to connect researchers with clinicians, donors & stake holders to help translate research efforts into evidence-based treatments for autism and its co-morbidities. It highlighted the need for multidisciplinary collaboration, detailed diagnostics and personalised treatment…

read more
Transcranial direct current stimulation tDCS – a novel treatment for autism?

Transcranial direct current stimulation tDCS – a novel treatment for autism?

One of the treatment modalities that has shown the greatest promise for reducing symptoms of autism in recent years is transcranial direct current stimulation (tDCS). The most recent study confirmed and expanded on the findings of previous investigations, which strongly indicate that tDCS could have positive effects on cognition, behaviour and physical health, and improve quality of life and autonomy for a large percentage of individuals with autism.

read more
Cannabis for Treating Core and Comorbid Autism Symptoms – Where are we at?

Cannabis for Treating Core and Comorbid Autism Symptoms – Where are we at?

Several studies published in recent months investigated the effects of cannabis-based products for treating autism. Although the studies were open-label and relatively small in scale, the overall results were overwhelmingly positive, with statistically significant improvements in social communication, language, restrictive/repetitive and challenging behaviours.

read more
Century-old drug offers new hope for autism treatment

Century-old drug offers new hope for autism treatment

A small double-blind, placebo-controlled trial shows dramatic effects of suramin as a treatment for autism. Improvements were seen in all three core features of autism: language, social interactions, and restricted or repetitive behaviours across multiple diagnostics in multiple tests in all who received the active treatments, absent in the placebo arm

read more
Higher rates of autism in children with various congenital disorders

Higher rates of autism in children with various congenital disorders

Children with Congenital Heart Disease, Tuberous Sclerosis Complex, Duchenne Muscular Dystrophy, Ehlers-Danlos Syndrome, Neurofibromatosis Type 1 suffer high rates of autism. Everolimus, an mTOR inhibitor with strong neuro-inflammation attenuating effects, reduces core autism symptoms in some children with TSC, epilepsy and autism…

read more

Keep informed - subscribe to our mailing list

We will email you autism-related news and updates. You can unsubscribe at any time.

No social media or google account? Sign up with your email address:

.
DISCLAIMER The purpose of this site is to provide information. No information on this website should be construed as medical advice. Neither article authors, associated charities, nor individual contributors take any responsibility or liability for any decision taken by site visitors as a result of the information contained herein or the external links provided. If you need medical advice, please seek it from a suitably qualified practitioner.

Privacy Policy  |  Terms and Conditions
© 2020 Thinking Autism | All rights reserved | Registered Charity: No. 1113628, Limited Company Registered in England: No. 5594787 | Registered address: International House, 24 Holborn Viaduct, London, EC1A 2BN | Contact tel. 07518131697